Hormonal rejuvenation is an approach aimed at restoring normal hormone levels in the body, which can decline with age. Hormonal therapy is used to slow down the aging process, improve overall well-being, maintain energy, cognitive function, and physical fitness.
As people age, there are natural changes in the levels of key hormones such as testosterone, estrogen, progesterone, melatonin, growth hormone, and others. These changes can lead to symptoms such as fatigue, decreased muscle mass, cognitive decline, depression, and poor skin quality.
The main hormones used in hormonal rejuvenation
Human growth hormone (HGH):
Role in the body: Human growth hormone plays an important role in cell regeneration, tissue growth, muscle mass maintenance, and metabolism.
Decrease with age: After age 30, growth hormone levels begin to gradually decline, which is associated with decreased muscle mass, poor skin condition, and a slower metabolism.
Hormonal correction: The installation of bioidentical growth hormone can help increase the level of HGH in the body, improve muscle tone, reduce fat mass and improve overall well-being. However, the use of growth hormone requires careful supervision of a doctor, namely in the selection of dosage.
Testosterone (for men and women):
Role in the body: Testosterone is important for maintaining muscle mass, bone density, sexual function, energy and mood. Decline with age: Testosterone levels in men begin to decline around age 30, resulting in decreased energy, decreased libido, loss of muscle mass, and increased fat mass.
Hormonal correction: Testosterone replacement therapy can improve physical condition, energy, sexual function, and quality of life in men with low testosterone. In women, low testosterone can also affect libido and mood, and weight gain. Correction with bioidentical androgen hormones helps to balance hormones and significantly improve both internal health and external appearance
Estrogen and progesterone (in women):
Role in the body: These hormones play a key role in the reproductive system, maintaining bone density, regulating mood, and metabolism.
Decline with age: In women, menopause causes a sharp decline in estrogen and progesterone levels, leading to symptoms such as hot flashes, mood changes, decreased bone density, dry skin, and decreased energy. Hormonal correction: Hormone replacement therapy using estrogen and progesterone helps reduce menopausal symptoms and prevent age-related changes such as osteoporosis, vascular changes.
Melatonin:
Role in the body: Melatonin is a hormone that regulates the sleep-wake cycle and also has an antioxidant effect.
Decline with age: Melatonin levels often decline with age, leading to sleep problems and overall poor health. Hormonal correction: Taking melatonin can improve sleep quality, help restore biorhythms, and have an antioxidant effect on the body. Regulates circadian biorhythms of wakefulness and rest.
Dehydroepiandrosterone (DHEA):
Role in the body: DHEA is a precursor to sex hormones (testosterone and estrogen) and affects the immune system, mood, energy, and sexual function.
Decrease with age: DHEA levels begin to decline with age, which can impact overall well-being, sexual function, and cognitive abilities.
Hormonal correction: DHEA is often used as a bioidentical hormone to increase energy, improve mood, and slow down the signs of aging.
In our practice, we use exclusively biohormonal therapy.
A bioidentical hormone pellet is a small implant containing bioidentical hormones that are chemically identical to the hormones produced by the human body. Pellets are used in hormone replacement therapy (HRT) to restore normal hormone levels in men and women, often used to treat age-related symptoms (such as menopause or androgen deficiency). They are implanted under the skin, where they slowly release hormones over several months.
How does a bioidentical hormone pellet work:
Subcutaneous implantation: The pellet is inserted under the skin into the fat layer, most often in the buttocks or thigh area, through a small incision. This is a procedure that is performed under local anesthesia and takes several minutes.
Gradual release of hormones: Once implanted, the pellet begins to gradually release hormones into the blood. These hormones (such as testosterone, estradiol, NADH, melatonin, etc.) enter the body over several months. The release process depends on the patient’s metabolic rate: the more active the metabolism, the faster the hormones are released.
Stable hormone levels: One of the advantages of pellets is that they provide a stable and constant level of hormones in the body. Unlike tablets or creams, which can cause sharp fluctuations in hormone levels (rapid absorption and elimination), pellets release hormones slowly and evenly.
Long-lasting action: Pellets usually last from 3 to 6 months, depending on the type of hormones and the patient’s metabolism. This means that daily use of hormonal drugs is not required, which is convenient for many people.
Advantages of bioidentical hormone pellets:
Natural hormones: Bioidentical hormones are identical in structure to the natural hormones produced by the body. This helps the body absorb them better and minimize side effects.
Gradual release: Pellets provide stable hormone levels over several months, avoiding the sudden fluctuations in hormone levels that can occur with creams, tablets or injections.
Long-lasting: Once the pellet is inserted, the patient does not need to take daily hormonal medications or have regular injections.
Personalization: Pellets can be made with individual dosages, depending on the needs of the patient’s body, making their therapy more precise and personalized. The body does not “select” the active dose of hormones from a bioidentical hormone pellet in the usual sense, but regulates the release of hormones based on biological mechanisms related to blood circulation and metabolism. Here’s how it works:
How a bioidentical pellet works:
Blood flow and metabolism: Hormones are released from the pellet gradually depending on the blood supply at the site of insertion. The higher the intensity of blood circulation in the tissues (for example, during physical activity or increased metabolism), the more hormones are released from the pellet into the blood. The body cannot directly regulate the dose of hormones, but the rate of release is partly dependent on physiological processes.
Passive release: The pellet slowly dissolves under the skin and releases small doses of hormones continuously. This occurs due to the slow destruction of the pellet material by enzymes and metabolic processes in the tissues. The more active the body and its metabolism, the faster the hormones are released.
The body’s need: The need for hormones can fluctuate depending on various factors: the level of physical activity, stress, cyclical changes in the body (for example, in women during the menstrual cycle) and other conditions. With higher activity of the body, blood circulation increases, and, accordingly, hormones are released faster, meeting the necessary needs.
Gradual dissolution of the pellet: The pellet is designed to release a stable dose of hormones over a long period of time (usually from 3 to 6 months). This ensures a constant but controlled level of hormones in the blood without sudden jumps. Since the pellet dissolves slowly, the body receives doses of hormones evenly, depending on its metabolic activity.
Why the body does not receive too many hormones:
Uniform release: The design of the pellet is such that it releases hormones gradually and evenly, avoiding situations where the body can receive an excessive amount of hormones in a short period.
Natural fluctuations in metabolism: The body regulates blood flow and metabolism depending on its needs (e.g. during physical activity, rest or stress), which indirectly affects the amount of hormones released into the bloodstream. For example, during greater physical activity or stress, more hormones may be released because the blood circulates more actively throughout the body.
Personalized dosage: Doctors select the dose of hormones in the pellet based on the individual characteristics of the patient: age, activity level, body weight and health status. This helps to minimize the risks of overdose and ensure optimal hormone levels for a particular person.
Recommendations
Hormonal correction for rejuvenation should be carried out only under the strict supervision of a doctor who can assess the patient’s condition, identify the need for such therapy and select the correct dosage. It is necessary to take into account the individual characteristics of the body, possible risks and potential side effects.