Non-surgical facial rejuvenation always attracts patients more, because it does not carry high risks of damage to the skin, nerve endings, the presence of postoperative scars, atrophic tissue, problems with hair growth, etc. Of course, the period during which you begin to pay close attention to your face is very important. If this is done systematically and regularly, then age-related changes in the skin and muscles are practically not noticeable, the skin is in good quality condition, the muscles are toned. Another thing is to remember about yourself when you are already over 50 and a lot of time has gone irrevocably, but you want to look beautiful and well-groomed.
The methods that we will talk about today do not represent competition to plastic surgery, this is an opportunity to preserve the youth of your skin and muscle frame for as long as possible.
Today we will not talk about cosmetic products, which are based on stabilized minerals, microelements and other components that can help our skin.
We will talk about the reserve of our youth and skin health, how to maintain it in a natural, natural way. All reserves in our body are limited, including the processes of regeneration and restoration of the skin. A certain starting point is the age of 30, then the skin begins to lose the volume of the necessary components of youth: collagen, elastin, hyaluronic acid, fat cells, the density of the intercellular matrix. As a result, such necessary and important processes as nutrition, hydration, restoration of the lipid layer begin to decrease, forming wrinkles, changing the morphotype and quality of the skin.An important element of the quality of our skin are fibroblasts, which also decrease by an average of 10-15% every 10 years after the age of 30. Yes, cell regeneration still occurs, but this process becomes slower, some cells with damage or mutation do not have the ability to restore lost functions.
FIBROBLASTS – THE SECRET OF UNLIMITED YOUTH
It is fibroblasts that can help constantly maintain the youthful age of the skin. Fibroblasts can be both your own and donor, everything depends on the age, quality of the skin, lifestyle of the patient. After all, the regenerative power to restore is important in fibroblasts, it is highest in donor samples or the skin of young patients. The older the patient, the lower the quality and regenerative power of such rejuvenation. After all, our cells remember all our breakdowns, have a shadow of our diseases and ailments, and if there are quite a lot of these factors, then even cultivation in the laboratory will not be able to improve the quality of such fibroblasts. Functionally active fibroblasts have a unique potential to restore and maintain the synthesis of the extracellular matrix of the skin, which results in elasticity, skin elasticity, this method of rejuvenation slows down the destructive processes of aging and cell death.

EXOSOMES AS PART OF FACIAL REJUVENATION THERAPY
In parallel with the introduction of fibroblasts, we use exosomes for skin regeneration and rejuvenation. Let’s say right away that these are extracellular vesicles that penetrate the cell nucleus, forcing it to restart the function. That is, not all skin cells are active and perform all the functions correctly. Time, environmental influences, habits, diseases – some cell families fail, then they weaken and lose the basic functions on which the youth and health of the skin depend. It is exosomes that can reboot these functions in those cells that have weakened and are losing functions.
In a lasting rejuvenation effect, the role of consistency and cyclicity is important, because we work only with facial skin, and all other organs and systems continue to age and lose basic functions: hormonal, metabolic, biochemical changes.

WHAT IS THE IMPORTANCE OF USING ENDOTHELIAL CELLS
Young skin is skin that is well nourished. The main source of nutrition is the vessels that carry micro and macroelements, moisture, and participate in all processes of synthesis of the necessary structural cells. But often during life patients can use different methods of rejuvenation (from hardware to surgical, also making injections of dense synthetic gels, damaging muscle tissue with threads or deep damage of laser, waves, needles). In these areas, inflammatory areas are formed first, then dense fibrous with pronounced damage to vascular branches.
That is precisely why endothelial cells (microvascular) are so important in these places to restore balanced nutrition of tissues and skin, eliminate atrophic areas of damage, make the skin healthy, and at the same time beautiful.

MITOCHONDRINAL COMPLEX FOR LIFE AND ENERGY OF THE SKIN
Energy is the main part of the youth of the whole organism. The skin is also no exception and needs energy intercellular exchange. It is the mitochondria that are responsible for the generation of energy in cells, the synthesis of ATP, thermoregulation, proper metabolism inside cells, oxygen supply. Also, the energy reproduced by mitochondria promotes the reproduction and growth of cells at any age, the removal of toxic substances from cells.

That is, it is definitely possible to achieve the most pronounced rejuvenation effect without surgical intervention, but it is important to start caring for and maintaining the youth of the skin before irreversible processes of ptosis of muscles and skin occur. Each patient is individual, and the rejuvenation program is made exclusively from the type of skin aging, age, medical history. In addition to the above methods, mesenchymal stem cells, fat cells, placenta cells, tissue metalloproteinase inhibitors, ribosomes for protein synthesis, etc. can also be used.
