Autism and autism spectrum disorders (ASD) result from disorders of brain development and are characterized by severe and pervasive deficits in social interaction and communication, as well as restricted interests and repetitive activities. ASD affects how children develop and how they perceive and interact with the world.
Autism is a spectrum disorder, so people with autism may experience mild to very severe symptoms. But it is a condition that lasts a lifetime and is often a fundamental part of the personality.
Treatment of autism is an increasingly important area. According to the US Centers for Disease Control and Prevention:
- 1 out of 59 children was diagnosed with autism spectrum disorder (ASD).
- Autism affects all racial, ethnic, and socioeconomic groups.
- Studies in Asia, Europe and North America have found incidence rates of ASD between 1% and 2%.
- Autism spectrum disorder (ASD) affects approximately 1-2% of the population worldwide and the number of people with autism is constantly increasing.
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Possible causes of autism.
The causes of autism are still poorly understood and subject to controversy, but research points to two key triggers:
- decreased oxygen levels in certain parts of the brain.
- chronic inflammation in the digestive tract caused by dysfunction of the immune system.
Other potential causes include Martin-Bell syndrome, brain tumors, brain swelling, missing metabolic enzymes, and measles in the mother during pregnancy.
Can autism be cured?
There is currently no cure for autism spectrum disorder. The doctor’s arsenal includes only methods of psychological rehabilitation and pharmacotherapy, which partially improve the condition of children with autism.
The hope for healing for patients with autism spectrum disorders comes only from the use of stem cells.
Why stem cells?
Stem cell treatment is complex and, for many diseases, still incomplete. These cells have the ability to transform into a wide variety of more specialized cells.
They can replace healthy cells of the digestive tract, brain, enzyme production systems, hormones, etc. with healthy ones. In addition, certain types of stem cells may reduce inflammation and may therefore be able to treat autism.
Stem cell therapy for autism suggests “rewriting” the body systems that cause autism.
Several studies suggest that in autism, intravenous and endolumbar administration of certain types of stem cells improves both the overall regulation of the immune system and the interaction of neurons in the brain.
Dr. Kurtzberg’s team at Duke University began its first clinical trial of stem cells for autism in 2014, analyzing the feasibility of autologous cord blood stem cell transplants into children with autism. Published results show significant improvements according to the Vineland Adaptive Behavior Scale (VABS). Moreover, Duke University and the Panama Stem Cell Institute conducted clinical trials using another source of stem cells – umbilical cord mesenchymal stromal cells.
Treatment of autism with stem cells
The use of umbilical cord blood to treat children with autism has exceeded all expectations. The cord blood showed immediate positive results: 70% of 125 children ages 2 to 8 had the behavioral improvements described by their parents and tracked by Duke researchers.
During the year, the children went to the medical center three times. They underwent a series of tests, such as autism assessments, MRIs and EEGs to track their brain activity. On the first trip, the children received cord blood transfusions along with intensive tests. Each child received from 1 to 2 billion cells intravenously. Six months later, and then a year later, the children returned for more tests and observations. Compared to the beginning of the study, the children’s vocabulary increased significantly, there were fewer repetitive actions and improved speech.
Dr Dawson said: “The study was very encouraging. We’ve really seen positive results.”
An example of another encouraging story of improvement after stem cell therapy:
Patient, Andrey, 10 years old, diagnosed with autism. For 10 years, the family could not come to terms with this diagnosis, so constant work with a psychologist, speech therapist, and physiotherapist was the basis of their daily work. Stem cell therapy and its results were a new discovery for the family, because they had not previously known about this type of treatment. But the desire to help a child, improve his life, increase his adaptation in society is stronger than any doubt.
The therapy was carried out on September 3, 2023, the cells were administered intravenously and endolumbarally. Hematopoietic cord blood cells, exosomes, and neural crest cells were introduced. The boy tolerated the therapy quite easily, the patient’s immune response was predictable and did not cause an aggressive reaction from the body such as (weakness, fever, lack of appetite).
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Within a month, the parents noted the first changes: Andrei could independently carry out the usual commands: go to the toilet, wash his hands, put on the necessary clothes, put an object in its place. A little later, his behavior in social places improved; he could quietly and calmly walk with his parents in the park, without hysterics and anxiety about passing people. The level of concentration and attention when working with teachers also increased, and he was able to pay more precise attention when working with curriculum. This is only an improvement for the first 2 months, then we are waiting for progress from Andrey and more significant results of improvement.
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