Type 2 diabetes has long been a true pandemic of the modern world, it affects more than 400 million people. This serious condition is associated with a decrease in insulin sensitivity and an increase in blood sugar levels. This can lead to various health problems such as:
Cardiovascular disease, including heart attack and stroke.
Damage to the kidneys can lead to chronic kidney failure and the need for dialysis.
Nerve damage, neuropathy, pain and loss of sensation in the limbs.
Damage to the eyes, leading to retinopathy and then loss of vision.
Diabetic foot and limb amputation.
Diabetic erectile dysfunction and infertility.
Other health problems such as infections, tooth loss, and acute hyperglycemia.
Traditional treatment for type 2 diabetes includes dietary changes, physical activity, medication, and blood sugar control. In some cases, insulin may be required. Doctors and scientists are constantly on the lookout for new treatments.
OBSERVE NEW TREATMENT PROTOCOL 2026:Stem Cells Treatment for Diabetes Type 1 and Type 2
Back in 2006, the first publications appeared about a significant reduction in insulin resistance and improvement in insulin sensitivity after the introduction of stem cells in patients with type 2 diabetes. Cell infusion during the early phase of the disease also contributed to the restoration of pancreatic β-cells. These data indicate that multiple processes and mechanisms are involved in the effectiveness of MSCs in alleviating hyperglycemia in type 2 diabetes mellitus.Stem cell therapy for type 2 diabetes is still considered experimental and is not widely available. Even after it, people with type 2 diabetes must continue to follow a certain lifestyle, diet, and regularly monitor blood sugar levels. So far, cell therapy provides only temporary relief for up to 5 years, removes concomitant disorders in the body caused by diabetes, prolongs and improves a person’s life, allows you not to increase the dose of a standard drug, but is not able to cure the disease forever.
On the other hand, research using stem cells to treat diabetes has shown promising results. Some potential improvements that may occur after stem cell treatment for type 1 or type 2 diabetes include:
Improving Insulin Production: Stem cells have the ability to differentiate into pancreatic β-cells, which helps to resume insulin production in the body.
Reduced insulin resistance and improved glucose uptake.
Reduced inflammation: Diabetes is often associated with chronic inflammation, which can contribute to insulin resistance and other complications. Stem cells have anti-inflammatory properties, which improves overall health.
Improving blood sugar control by restoring normal insulin production and reducing insulin resistance reduces the risk of complications associated with diabetes.
Restoring the functioning of organs already affected by diabetes by replacing damaged cells, growing new blood vessels, and activating the body’s own recovery processes.
READ MORE ABOUT REAL CASE STUDY: Diabetes Type 1/Type 2 – Stem Cells Therapy : Case Study
The main indicator of the effectiveness of cell therapy is that some patients with type 2 diabetes may refuse insulin injections or significantly reduce its dose, almost all have a decrease in the level of glycated hemoglobin and C-reactive protein.
For the treatment of type 2 diabetes, mesenchymal stem cells (MSCs) of an adult organism are most often used – obtained from the umbilical cord, placenta, bone marrow, adipose tissue. They are safe and most natural.Interestingly, cord blood has a positive effect on the condition of both type 2 and type 1 diabetics. Australian researchers treated at-risk children (born to parents with type 1 diabetes) with their own cord blood at the first symptoms of diabetes or for prophylactic purposes in the first year of life. In most children, diabetes has stopped progressing. Of course, these children need long-term follow-up.
Virus-modified cells (induced stem cells – iPSC) are also being studied, which are able to purposefully repair or replace insulin-producing pancreatic β-cells. So far, such studies are not widely used because of their cost.
Several hundred clinical trials of the treatment of diabetes mellitus with the help of stem cells have been registered in the world. Some of them have already been completed and their results have been published:
In 2014, the journal Diabetes Care published results on the use of autologous (cells from the patient’s own) bone marrow stem cells (BMSCs) in patients with type 2 diabetes. The study found that the therapy significantly improved insulin sensitivity and reduced inflammation in treated patients.
MORE INFORMATION HERE: Can stem cells treatment help with Diabetes?
A 2017 study published in the journal Diabetes Therapy evaluated the use of allogeneic (donor) umbilical cord mesenchymal stem cells (UC-MSC) in patients with type 2 diabetes. The study showed that UC-MSC therapy was safe and resulted in improved glucose control and reduced inflammation in patients.
In China, CAR-T (Shanghai) Biotechnology Co., Ltd. a study was conducted on the use of stem cells derived from human deciduous teeth. The age of the most diabetic patients was from 45 to 65 years. Unfortunately, the dose of cells was not enough to obtain a sustainable result, but positive changes in sugar control were noted in most patients.
In 2022, the results of the NEPHSTROM study for diabetic patients with severe kidney disease were presented. The study was conducted jointly at leading medical centers in Galway, Bergamo, Birmingham and Belfast. The patients received injections of mesenchymal stem cells from the bone marrow of healthy donors. The study showed that cell therapy can slow the progression of progressive kidney disease, which affects a third of diabetic patients, thus avoiding dialysis and even kidney transplantation.
As can be seen from this small list of studies, the safety and efficacy of different types of stem cells for the treatment of type 2 diabetes are being studied. Stem cells obtained from a young healthy donor remain the best choice. This can be material collected after the birth of a child – cord blood, umbilical cord, placenta as the cheapest, ethically and painlessly obtained sources of stem cells. Also after the age of 18, it makes sense to save your own mesenchymal stromal cells from fat, which can help in the treatment of the whole family. The quality and efficiency of fat cells directly depend on the age and health of a person.
Please note that cell therapy opens up the possibility of personalized treatment and access to modern therapies. Take care of yourself and your family, save stem cells in time.Detailed advice on stem cell preservation or treatment can be obtained by calling +38 097 252 48 76 or write on email info@bioage.com.ua