Stem cells are the precursors of all cells and tissues of the body, they maintain their numbers through division and turn into different types of cells. Throughout life, cells divide and replace those that have been damaged – this mechanism ensures the life and development of the organism. All our “breakdowns” are quickly restored thanks to stem cells. Unfortunately, with age, their quantity and quality in the human body decreases. With a decrease in the number of stem cells and a decrease in the level of their activity, the body copes with diseases worse, recovers more slowly and ages.
Umbilical cord blood, umbilical cord and placenta.
Contains a large number of young stem cells, which are safer for use, less often cause complications and rejection during treatment. Umbilical cord blood, placenta and umbilical cord are sources of young hematopoietic and mesenchymal stem cells, which are responsible for hematopoiesis, regeneration and, in particular, for human immunity at any age.
Successes in the use of umbilical cord mesenchymal stem cells ( 1999):
- About 2000 patients with Crohn’s disease have been successfully treated in the world – reduced inflammation, pain syndrome, diarrhea, accelerated healing of ulcers.
- Results of treatment of 172 patients with severe rheumatoid arthritis, not amenable to conventional therapy, have shown the effectiveness of the use of mesenchymal stem cells of the umbilical cord.
- Intracoronary administration of stem cells of the umbilical cord in systolic heart failure increases the left ventricular ejection fraction and the distance that the patient is able to travel without suffocation.
- The results of treatment of 50 patients with decompensated liver cirrhosis showed that transplantation of umbilical cord stem cells into the liver tissue leads to a decrease in edema and an increase in the protein-producing function of the liver
- Umbilical cord stem cells, when injected intravenously, accumulate in the cells of the affected joints, restoring them .
- Stem transplant umbilical cord cells in type 2 diabetes mellitus made it possible to cancel insulin injections in half of the patients for a period of 2 to 4 years
Bone marrow and peripheral blood. A well-known source of stem cells is the human bone marrow, from which the history of the successful use of stem cells begins. Stem cells from bone marrow and peripheral blood.
The activity of stem cells from adipose tissue and neural crest depends on the patient’s age, the presence of severe diseases and bad habits. Most often used in plastic and reconstructive medicine.
Stem cells are progenitors of specialized cells, such as blood, skin, liver, mucosa and other cells that organs and tissues are made of. Since specialized cells can only live for a certain period of time, their count in the body should be maintained continuously. Acting as a repair system, stem cells can asymmetrically divide producing a mother cell ensuring self-replication and a new cell capable of differentiation into a specialized cell.
Stem cells vary by their differentiation potential, which is the highest for the fertilized egg, or zygote, capable of differentiation into any cell type of the body and extraembryonic tissues. Over the next 9-12 weeks, this potential is maintained. While they develop, stem cells become more specialized, and their differentiation potential decreases.
In our clinic, we use 9-12 week old fetal stem cells with very high differentiation potential. They can differentiate into the wide range of cell types within the certain germ layer – ectodermal, endodermal or mesodermal. Moreover, the stem cells we use have higher proliferative potential compared to other types of stem cells (adult stem cells, cord blood stem cells, etc.)
At the same time, the stem cells we use have already undergone specialization in the germ layers, lost their capacity for uncontrolled growth, and we “know for sure” what cell or tissue type they should differentiate into. Fetal stem cells (9-12 weeks old) are different from embryonic stem cells (4–5 days post fertilization) capable of uncontrolled growth that can result in teratomas. We have no cases or history of post-treatment tumor development in our patients.
As we age, the stem cell count in the body decreases. For a newborn, the stem cell ratio stands at 1/10,000, for teenagers at 1/100,000. By the age of 50, it amounts to 1/500,000, and by the age of 70, only to 1/1,000,000. Therefore, the issue of cell pool replenishment and activation of one’s own stem cells is the key to finding solutions on how to live longer, stay young, and treat a wide range of diseases caused by cell count depletion.